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Vertex Pharmaceuticals

VRTXHealthcare

Generated Aug 19, 2026, 11:14 PM UTC

analytical score -2

VRTX (Vertex Pharmaceuticals) analytical snapshot. Revenue grew +8.9% YoY to $12.00B. 5-year revenue CAGR +9.6%; 10y CAGR +24.2%. Net margin at 32.94% (contracting ▼). Market cap $139.93B at $552.06 per share. Trailing P/E 36.04, P/S 11.66, P/B 6.91. EV/Operating income ≈ 32.08 (EV $133.89B). Risk: Low. Macro: Risk-on · Supportive. Composite analytical score -2 (data confidence 83%). Descriptive analytics from public filings — not investment advice.

Market cap
$139.93B
253.46M shares
Price
$552.06
NMS
P/E (ttm)
36.04
Revenue (FY)
$12.00B
YoY +8.9%
Net margin
32.94%
▼ 4.26pp
Free cash flow
$3.19B
26.61% margin
Risk level
Low

Free SEC analysis

— computed from SEC filings, free to read
Free previewRegulatory Analyst

Filings & Ownership

Regulatory Analyst
score 10Stable
80% conf

Latest quarterly report (10-Q) filed Aug 4, 2026. 6 recent 8-K material-event filings in the index. Recent insider Form 4s: 0 buy vs 0 sell transactions.

  • Latest quarterly report (10-Q) filed Aug 4, 2026.
  • 6 recent 8-K material-event filings in the index.
  • Recent insider Form 4s: 0 buy vs 0 sell transactions.
  • 6 recent 13D activist/beneficial-ownership filings — potential catalyst.
  • 14 recent 13G passive institutional ownership notices.
Latest 10-K
Latest 10-Q
Aug 4, 2026
8-K (recent)
6
Insider net
0B/0S
13F filers
Activist 13D
6
Recent 8-K material events
DateFormDescription
Aug 3, 20268-K8-K
Jul 7, 20268-K8-K
May 13, 20268-K8-K
May 4, 20268-K8-K
Apr 29, 20268-K8-K
Mar 31, 20268-K8-K
Free previewSEC Filing Analyst

SEC Filing Deep-Analysis

SEC Filing Analyst
score -80Deteriorating
68% conf

6 risk signal(s), 1 watch item(s) detected from XBRL filing diff analysis. Revenue grew +8.9% but receivables grew +27.6% — the receivables-to-revenue gap suggests growth may be partially driven by extended credit terms rather than genuine demand. If DSO continues to rise, a revenue reversal or bad-debt charge could follow.

  • Receivables outpacing revenue: Accounts receivable grew +27.6% YoY vs revenue growth of +8.9%. The +18.6% spread suggests extended credit terms, channel stuffing risk, or collection deterioration. Investigate the allowance for doubtful accounts and DSO trend.
  • Inventory buildup exceeds sales growth: Inventory grew +39.9% vs revenue +8.9%. Excess inventory may signal weakening demand, potential write-downs, or supply chain overcommitment. Watch gross margin for discounting impact.
  • NEW: Going concern doubt in latest filing: The term "going concern" "substantial doubt" appears in recent 10-K/10-Q filings but was NOT present in the prior 24-month period. This is a new risk disclosure that warrants attention. Found in 3 filing(s).
  • Material weakness in internal controls: The term "material weakness" "internal control" appears in 2 recent filing(s) (vs 2 in the prior period). This risk language is ongoing.
  • NEW: Substantial doubt about ability to continue in latest filing: The term "substantial doubt" "ability to continue" appears in recent 10-K/10-Q filings but was NOT present in the prior 24-month period. This is a new risk disclosure that warrants attention. Found in 3 filing(s).
  • Restatement of financial statements: The term "restatement of" "previously issued" appears in 5 recent filing(s) (vs 2 in the prior period). This risk language is ongoing.
  • Endogenous analysis: Revenue grew +8.9% but receivables grew +27.6% — the receivables-to-revenue gap suggests growth may be partially driven by extended credit terms rather than genuine demand. If DSO continues to rise, a revenue reversal or bad-debt charge could follow.
  • 10 new XBRL disclosure(s) in latest filing — expanding reporting scope.
  • 20 disclosure(s) dropped from prior year — reduced reporting granularity.
  • 3 new risk-language term(s) detected in filing text: Going concern doubt, Substantial doubt about ability to continue, Off-balance sheet arrangements.
  • Ongoing high-severity risk language: Material weakness in internal controls, Restatement of financial statements.
Revenue
$12.00B
+8.9% YoY
Operating income
$4.17B
+1891.9% YoY
Net income
$3.95B
+838.1% YoY
Operating cash flow
$3.63B
+837.2% YoY
Capex
$437.6M
+47.0% YoY
Total assets
$25.64B
+13.8% YoY
Total liabilities
$6.98B
+13.9% YoY
Cash & equivalents
$5.08B
+11.3% YoY
Filing quality score
80/100
10 new disclosures
SEC XBRL metric changes (latest annual vs prior)
MetricPrior yearLatest yearChange% Change
Revenue$11.02B$12.00B$981.2M+8.9%
Operating income$-232.9M$4.17B$4.41B+1891.9%
Net income$-535.6M$3.95B$4.49B+838.1%
Operating cash flow$-492.6M$3.63B$4.12B+837.2%
Capex$297.7M$437.6M$139.9M+47.0%
Total assets$22.53B$25.64B$3.11B+13.8%
Total liabilities$6.12B$6.98B$853.6M+13.9%
Cash & equivalents$4.57B$5.08B$515.2M+11.3%
Stockholders equity$16.41B$18.67B$2.26B+13.7%
Inventory$1.21B$1.69B$481.4M+39.9%
Accounts receivable$1.61B$2.05B$443.4M+27.6%
R&D expense$1.83B$3.05B$1.22B+66.8%
SG&A expense$1.46B$1.75B$288.8M+19.7%
Interest expense$58.5M$58.2M$-351000-0.6%
XBRL disclosure changes (new vs dropped concepts)
TypeConcepts
AddedAvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax, AvailableForSaleDebtSecuritiesAmortizedCostBasis, AvailableForSaleSecuritiesDebtMaturitiesAfterFiveThroughTenYearsFairValue, AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue, AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue, AvailableForSaleSecuritiesDebtSecurities, EquitySecuritiesWithoutReadilyDeterminableFairValueAmount, InvestmentIncomeNet, ProceedsFromCollectionOfNotesReceivable, RealizedInvestmentGainsLosses
RemovedAccruedRoyaltiesCurrent, AdvertisingExpense, AmortizationOfIntangibleAssets, BusinessCombinationContingentConsiderationLiabilityNoncurrent, CapitalizedComputerSoftwareAmortization1, CapitalizedComputerSoftwareGross, CashFlowHedgeDerivativeInstrumentAssetsAtFairValue, ContractWithCustomerLiabilityRevenueRecognized, CurrentFederalTaxExpenseBenefit, CurrentForeignTaxExpenseBenefit
Risk language in filing text (EDGAR full-text search)
TermSeverityRecentPriorStatus
Going concern doubthigh30NEW
Material weakness in internal controlshigh22Ongoing
Substantial doubt about ability to continuehigh30NEW
Restatement of financial statementshigh52Ongoing
Impairment chargemedium55Ongoing
Restructuringmedium52Ongoing
Off-balance sheet arrangementsmedium50NEW
Related party transactionslow51Ongoing
Filing signal breakdown
Red flags: 6
Positive: 0
Watch: 1
Red flags
Positive
Watch
Free previewFundamentals Analyst

Fundamentals

Fundamentals Analyst
score 35Improving
80% conf

Revenue grew +8.9% YoY to $12.00B. 5-year revenue CAGR +9.6%; 10y CAGR +24.2%. Net margin at 32.94% (contracting ▼).

  • Revenue grew +8.9% YoY to $12.00B.
  • 5-year revenue CAGR +9.6%; 10y CAGR +24.2%.
  • Net margin at 32.94% (contracting ▼).
  • Return on equity 21.18%, ROA 15.42%, ROIC 22.36%.
  • Gross margin 0.00%, operating margin 34.77%.
  • Free cash flow margin 26.61% ($3.19B).
  • Net income up ▲ +838.1% YoY.
  • Debt/equity 0.01, current ratio 3.19, net debt -$6.04B.
  • Asset turnover 0.44 — capital efficiency.
Revenue (FY)
$12.00B
YoY +8.9%
Net margin
32.94%
▼ 4.26pp
ROE
21.18%
ROA 15.42%
ROIC
22.36%
EPS (diluted)
$15.32
FY2025
Free cash flow
$3.19B
26.61% margin
Debt / equity
0.01
Cash $6.14B
Current ratio
3.19
Equity $20.25B
Annual fundamentals — up to 10 years (SEC 10-K, US-GAAP)
FYRevenueRev YoYGross%Op%Net%FCFROE%
2024$11.02B+11.7%0.00-2.11-4.86-$790.3M-3.26
2025$12.00B+8.9%0.0034.7732.94$3.19B21.18
Quarterly revenue trend (last 6 quarters, SEC 10-Q)
Quarter endRevenueYoYQoQNet margin
Jun 30, 2016$431.6M+159.9%-14.95%
Sep 30, 2016$413.8M+33.6%-4.1%-9.39%
Mar 31, 2017$714.7M+79.5%+72.7%34.66%
Jun 30, 2017$544.1M+26.1%-23.9%3.31%
Sep 30, 2017$578.2M+39.7%+6.3%-17.81%
Mar 31, 2018$640.8M-10.3%+10.8%32.81%
+8 more years of history, charts & full breakdown Pro

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— score, signals & key metrics shown; full reasoning locked

Valuation

Valuation Analyst
score -50Deteriorating
95% conf

Market cap $139.93B at $552.06 per share. Trailing P/E 36.04, P/S 11.66, P/B 6.91. EV/Operating income ≈ 32.08 (EV $133.89B).

  • Market cap $139.93B at $552.06 per share.
Market cap
$139.93B
253.46M shares
P/E (ttm)
36.04
P/S
11.66
P/B
6.91
EV
$133.89B
Intrinsic (DCF)
$216.76
-60.7% vs price
ProFull breakdown & reasoning locked

Price & Technicals

Technical Analyst
score 65Improving
85% conf

Price $552.06 — uptrend (above 200-DMA); 1-month momentum positive. RSI(14) 74.82 (overbought).

  • Price $552.06 — uptrend (above 200-DMA); 1-month momentum positive.
Price
$552.06
NMS
RSI(14)
74.82
50-DMA
$486.13
200-DMA
$458.52
Volatility (ann.)
28.39%
52w range
$374.17–$553.69
-0.3% from high
ProFull breakdown & reasoning locked

Macro & Rates

Macro Analyst
score 30Improving
80% conf

Risk-on · Supportive. Real GDP growth 1.50% (quarterly, as of Apr 1, 2026). CPI inflation +3.3% YoY. Fed funds rate 3.63%, 10Y Treasury 4.71%.

  • Market regime: Risk-on · Supportive.
GDP growth
1.50%
CPI (YoY)
+3.3%
Fed funds
3.63%
10Y yield
4.71%
10Y−2Y
0.46pp
Unemployment
4.10%
ProFull breakdown & reasoning locked

Risk Scorecard

Risk Analyst
score 15Stable
90% conf

Composite risk Low. Leverage debt/equity 0.01 (low). Liquidity current ratio 3.19 (adequate).

  • Composite risk: Low.
Risk level
Low
Debt / equity
0.01
Current ratio
3.19
Margin stdev
198.89pp
Cash / assets
22.40%
Liab / assets
26.17%
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Macro exposure

Defensive · Low sensitivity
Neutral

Macro regime: Risk-on · Supportive. Vertex Pharmaceuticals is a defensive name (low macro sensitivity) — a supportive backdrop, though defensives lag risk-on tapes.

Macro regime
Risk-on · Supportive
Yield curve
Normal
VIX
15.84
Fed funds
3.63%
CPI YoY
+3.3%

Analytical read

deterministic preview

Revenue grew **+8.9%** YoY to $12.00B..

Risk
Low
Macro regime
Risk-on · Supportive
Macro exposure
Neutral
Descriptive analytics from public filings and macro data — not investment advice.

Peer comparison

Defensive group

How VRTX stacks up against tracked peers with similar macro sensitivity — by analytical score and macro exposure.

CompanyScoreMacro
DexCom Inc. DXCM19Neutral
Bristol-Myers Squibb BMY19Neutral
Eli Lilly & Co. LLY17Neutral
HCA Healthcare HCA9Neutral
Gilead Sciences GILD8Neutral
Johnson & Johnson JNJ8Neutral
Abbott Laboratories ABT7Neutral
Biogen Inc. BIIB7Neutral
Intuitive Surgical Inc. ISRG7Neutral
Coca-Cola Co. KO6Neutral
Zoetis Inc. ZTS6Neutral
Thermo Fisher Scientific TMO3Neutral
Regeneron Pharmaceuticals REGN3Neutral
Danaher Corp. DHR1Neutral
Merck & Co. MRK0Neutral
Illumina Inc. ILMN0Neutral
Colgate-Palmolive CL-2Neutral
Vertex Pharmaceuticals VRTX● you-2Neutral
AbbVie Inc. ABBV-5Neutral
Procter & Gamble PG-7Neutral
CVS Health Corp. CVS-8Neutral
Mondelez International MDLZ-10Neutral
Amgen Inc. AMGN-10Neutral
Cigna Group CI-11Neutral
Kroger Co. KR-12Neutral
Costco Wholesale COST-14Neutral
Walmart Inc. WMT-14Neutral
Pfizer Inc. PFE-15Neutral
PepsiCo Inc. PEP-16Neutral
Sysco Corp. SYY-16Neutral
Hershey Co. HSY-17Neutral
Kimberly-Clark Corp. KMB-18Neutral
Moderna Inc. MRNA-21Neutral
UnitedHealth Group UNH-25Neutral